Emergency crews cleared the eastbound lanes of Highway 72 near Moores Mill Road following an early morning crash.
The crash happened just before 7:30 Monday morning.
Don Webster, spokesperson for Huntsville Emergency Medical Services Inc. (HEMSI), confirmed three patients were taken to the hospital.
One adult was transported to the hospital with serious injuries, a child and a second adult were also taken to the hospital for non-life threatening injuries.
It took crews about an hour to clear the scene and get traffic moving again.
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