Memorial Parkway traffic was shut down on the south side between Oakwood Avenue and University Drive after a wreck involving three vehicles, police said.
The wreck happened around 2 p.m., according to Huntsville police. Police were able to open lanes around 3 p.m.
One of the vehicles ran off the parkway and flipped over, landing upside down.
Police said no one was injured.
The cause of the wreck is under investigation.